LIQUID HANDLING ROBOTS RELIEVE PRESSURE ON LABS

Challenge

Demand for Flow Robotics’ liquid handling robots is growing steadily as more pharmaceutical and medical laboratories seek to move from manual to automated biological sample handling and pipetting processes to run more efficiently and handle growing pressure. The Danish manufacturer needed a high-performance platform to help scale up production of its robots and accelerate its product development processes.

Solution

Flow Robotics found the answer in the 3DEXPERIENCE platform on cloud, which it uses across its business to manage all product development data and define a common working environment for multidisciplinary collaboration. The product lifecycle management (PLM) platform now serves as a central repository for drawing templates and a standard components library, while supporting automatic bill of materials generation.

Benefits

Backed by the 3DEXPERIENCE platform, Flow Robotics has improved its ability to compete in an innovative market, while being able to create and maintain structure as its business continues to expand. The company is already saving time and reducing costs by working more efficiently. Its team benefits from the ability to produce better designs with fewer mistakes, communicate more effectively, improved visibility of project statuses and reduced administrative tasks.

LIQUID HANDLING ROBOTS RELIEVE PRESSURE ON LABS

In life-science laboratories and hospitals across Europe, a team of robots is helping to alleviate the strain on bioanalysts as they process thousands upon thousands of COVID-19 tests per day. Collecting, preparing and analyzing the virus samples is usually very manual and repetitive – a physically demanding, intensive task that involves mixing specific quantities of reagents and liquids using pipettes. Thanks to flowbot™ ONE pipetting robots, developed by Danish manufacturer Flow Robotics, laboratories can now easily automate part of the testing process, speeding up the time it takes to produce results and reducing pressure on their staff. However, PCR analyses are only one area of the applications of flowbot™ ONE.

High workloads and physically challenging conditions have long been an issue for laboratory professionals. Flow Robotics estimates that around half of medical lab technicians carry out the same arm movements for at least a quarter of their working day. Meanwhile, the American Society for Clinical Pathology reported that 85% of laboratory professionals feel burnt out; 36% struggle with inadequate staffing; and 32% face a heavy workload and pressure to complete all testing on time.

The flowbot™ ONE pipetting robots have been designed specifically to reduce physically demanding pipetting tasks for laboratory personnel and minimize the risk of human error and contagion in the process. The robots are paving the way for a more sustainable lab setup, where humans and robots work in parallel to avoid work-related injuries and operate more efficiently. In the COVID labs, the robots pipette the live virus, handling several samples simultaneously, all working from a predefined pipetting pattern.

“Our aim when we started was to disrupt the way that liquid handling is performed in life sciences companies around the world,” said Steen Vester, chief technology officer at Flow Robotics. “Laboratories tend to have lots of manual, repetitive tasks and are looking for ways to become more efficient. Our robots work alongside people, so they don’t get overburdened and develop strain injuries or become exposed to live virus samples. The robots deliver in terms of accuracy too. When you’re manually handling pipettes for hours, it can become difficult to dispense the exact amount of liquid every time. But this isn’t the case for a robot. It doesn’t get tired and make those kinds of mistakes. The psychological and physical savings we deliver are far from insignificant.”

Versatile and affordable, Flow Robotics robots can be used for numerous laboratory applications. Unilabs in Copenhagen, for example, uses the robots to dilute blood samples and dispense them onto microtiter plates as it screens sclerosis patients all over the world for diagnostic analysis.

“We’ve made it possible for lab technicians without any programming experience to learn how to set up the robots within an hour,” Vester said. “Often, these labs have a protocol and you can set that up on one of our robots in a couple of minutes.”

Orders for the affordable, user-friendly liquid-handling robots are growing fast as more laboratories become aware of the potential to speed up their processes and better support their staff.

“We want to put our pipetting robots into the hands of people in the labs to support them and avoid strenuous tasks,” Vester said. “Existing machines on the market are more focused on full automation, whereas we want to help create workplaces where robots and people work alongside each other. For that, the robots need to be adaptable, affordable, easy to program and very user friendly.”

As Flow Robotics scales up production, it realized it needed a powerful technology platform to bring order and visibility to its product development processes and, very much like its own robots, help make workflows more efficient. The company opted for the 3DEXPERIENCE® platform on cloud and is already achieving noticeable benefits.

“We couldn’t continue to grow the way we have without the support of the 3DEXPERIENCE platform,” said Per-Arne Jönsson, senior mechanical engineer at Flow Robotics. “As we’ve brought more engineers on board and expanded across the company, we needed a centralized communication platform to establish a common understanding, ensure everyone is working from the same data and help multiple disciplines work together. In terms of communication, we need a straight line instead of going around in circles. Our processes should follow a formal flow and the platform helps us to do that.”

SUPPORTING A FAST-GROWING BUSINESS

Flow Robotics’ team has expanded rapidly as demand for its robots accelerates. What used to be a case of a couple of engineers working alongside each other has turned into an increasingly complex operation as more people join the production, purchasing and R&D departments. It’s meant that the company has had to define new processes and workflows to achieve effective multidisciplinary collaboration.

“Within 20 weeks we were running our first projects directly in the platform, using it for automatic bill of materials (BOM) generation, drawing templates and sorting standard components within a material database,” Jönsson said. “We’ve balanced our processes and ways of working to use as much of the native 3DEXPERIENCE functionality as possible.”

Key to the success of the rollout was Flow Robotics’ partnership with Dassault Systèmes value added reseller X10D Solutions, which worked closely with the manufacturer to define its processes and implement the PLM platform.

“The first meeting we had with X10D really set the bar for what was to come,” Jönsson said. “There was no doubt that the partner was genuinely interested in helping us out. They spent a lot of time being there for questions. It felt like a joint venture with strong commitment and a can-do attitude, and they have been there for us throughout. It has made a huge difference to the end result and speed of implementation.”

“We couldn’t continue to grow the way we have without the support of the 3DEXPERIENCE platform.” – Per-Arne Jönsson, Senior Mechanical Engineer, Flow Robotics

Critically, X10D challenged Flow Robotics to rethink its way of working.

“X10D helped us develop a more balanced view and changed our mind about our processes in minor and major ways,” Jönsson added. “We didn’t know the platform before, so we trusted them to help us. Now, when we go into new projects, our users access, consume and share data in a very different way to before. It’s much easier.”

Opting for a cloud deployment also allowed Flow Robotics to get up and running quickly.

“It made sense for our business on so many levels,” Jönsson said. “There are numerous requirements for these on-site installations; I have yet to see a company succeed in that without interruption. For us, it was really important that we could hand over some of that IT management to the professionals with a lot more resources and skills. It’s great that we don’t have to worry about data security; we can trust Dassault Systèmes to handle that.”

FREEING MINDS UP FOR INNOVATION

Now that Flow Robotics has transferred all its legacy data into the 3DEXPERIENCE platform, it has begun handling new projects natively in the platform.

“Our goal has been to maximize the use of documentation and minimize administration, and we’re already seeing a benefit,” Jönsson said. “We can have discussions on a different level; people can see what we’ve discussed in meetings; and everyone can access the same data. It’s an ongoing journey for us. We were cross functional before, but now we have more people and we can give them an opportunity to go and look at stuff independently or brainstorm within small teams.”

Through this greater level of transparency and ease of access to information, Flow Robotics’ growing team is empowered to be more innovative.

“We have a lot of innovative people here,” Jönsson said. “When you have an efficient tool that allows you to focus on your work and not on documenting it, it makes your task easier and more fun. My aim is to have my engineers spending 98.5% of their time doing development and 1.5% doing documentation.”

“I wanted us to have a pure database setup from the very beginning and that’s what the 3DEXPERIENCE platform gives us,” Jönsson added. “Now, for example, the search and find feature is very easy to use; you can pull up the result you need without losing loads of time. The bottom line is we want to help our people focus on developing great customer-oriented products.”

Using customized dashboards and widgets, engineers can choose what information they want to see that’s relevant to them, allowing them to work smarter and faster.

“The flexibility of the web interface is really starting to pay off,” Jönsson said. “It’s brilliant to have the opportunity to build dashboards for specific use cases. I made one of our service engineers giggle with pleasure when I was able to create a dashboard with widgets catered to his needs within just ten minutes. I know that the possibilities in the platform are basically endless, but it brings a smile to your face when you can very quickly leverage the data you have painstakingly created in such a way that a colleague’s work tasks become easier and more efficient.”

About the solution

Engineered To Cure delivers a data-driven and model-based engineering platform that facilitates collaborative design and development of robotics and tools for the life sciences industry using best-in class apps and processes for 3D design, systems engineering, multiphysics simulations, and virtual modeling. Using this solution, designers and engineers can rapidly explore new designs, virtually test promising designs in real-world usage scenarios, and validate optimal designs against product requirements and business objectives.

Benefits:

• Develop agile product portfolios and processes that respond fast to market demands
• Increase innovation bandwidth and success rates through collaborative use of validated models and methods
• Reduce cost and time of new product development
• Deploy a systematic approach to design robust, safe and personalized robotics and devices

17/04/2023